"CTP; invented from the manufacturing technology of pharmaceutical excipient"
"Through the research of functionality of CTP for beauty and locomotive syndrome fields, we have advanced our study to preventive health care."
Jellice Co., Ltd. succeeded in creation of "Collagen Tripeptide (CTP)" which is a collagen-derived functional component dramatically different from other conventional collagen supplements by applying our techniques of production and development of gelatin/collagen that have been cultivated through years of research and development. We have been focusing on and investigating various functions of this excellent "Tripeptide": promotion of type I collagen and hyaluronic acid production for beautifying skin, promotion of collagen production and osteogenesis, and preventive/improving effect on knee osteoarthritis which are highly expected merchandise for resisting locomotive syndrome. Recently, we pursued the new functionality of CTP which is required in the preventive health care field such as preventive/improving effect on pruritus cutaneus caused by arteriosclerosis or dry skin, photo-aging caused by ultraviolet rays, etc., and atherosclerosis.
In an increasingly aging society, we feel it is our mission to support all the people so as to enable them to have a comfortable and healthy life by means of development of healthy supplements.
Vital protein for homeostasis of life
Collagen is found mainly in the skin, bones, joints, tendons, ligaments and blood vessels, and accounts for 30% of the entire protein content in the body, Collagen plays a crucial role for maintaining structure and exercising the functions of above tissues. In other words, most of the organs and tissues can hardly maintain those forms or work properly if collagen in the body is damaged by any physicochemical cause, or is decomposed/ destroyed by microorganisms or enzymes in the body. Moreover, if a collagen tissue suffered any morphological damage (rupture of skin, bone fracture, arthralgia, and bleeding, etc.) or any functional disorder (hepatic failure, renal failure and cardiopulmonary failure, etc.) in the body, the homeostasis is destabilized and it leads the person to a life crisis. Collagen is a very important component to maintain homeostasis of our life.
CTP greatly contributes to homeostasis
Collagen is composed of a chain of tripeptides (Gly-X-Y, hereinafter called CTP) which is a minimum unit of collagen. If we compare collagen to a jigsaw puzzle, CTP would be each puzzle piece. If CTP, a minimum unit of collagen, is found within the blood or the fluid in the body, it means there has occurred an injury, degradation or destruction of some collagen which forms part of some organ or tissue of that person. In that case, a "danger signal" is alerting the person that they may be unable to sustain his/her homeostasis. In fact, a recent study reported that a slight amount of CTP exists in human (a normal healthy person�s) blood. That is to say, while collagen tissues are regenerated, it is possible for some tissues or organs to be injured or decomposed.
Base on this knowledge, we have come to think that "While CTP represents a "danger signal" which alerts us to a crisis of life, it also should be a factor which maintains homeostasis (homeostatic factor) for humans" and have been getting more and more interested in the importance of the existence of CTP. We hope you realize a part of the amazing potential of CTP by looking at the data and the evidence in this scientific site.
Universality and safety of CTP
Don�t you think it strange that CTP or CP can exert this functionality and effect-efficacy in the human body despite being derived from pigs or fishes? This shows the universality of CTP. 29 kinds of collagen have been discovered so far, and those amino acid sequences are all different. Even in the same kind (type) of collagen, the amino acid sequence differs depending on the derivation - pigs, fishes, or humans. However, when it is made smaller into CTP, which is the minimum unit of various collagens (a basic unit: Gly-X-Y), every kind (type) of CTP which was derived from animals, fishes, and humans has the same sequence of 3 amino acids. Therefore, every CTP is regarded as the same component and acknowledged as autologous (self) in the human body. This is exactly seen from the scientific evidence that CTP has high safety. (Our research shows that CTP also has very low antigenicity, allergenicity and immunogenicity.) As mentioned above, CTP derived from pigs or fishes can work in the human body, because it has the same components as humans� CTP. In addition, the opposite case was revealed by our collaborative research with veterinarians and researchers at universities - that means CTP which is efficacious for the human body also exerts the same effect when it is administered to various animals such as mice, rats, rabbits, giraffes, elephants, etc. "The universality of CTP" which means that every CTP has "identical components" beyond the border of individual species has been shown.
Contribution to healthy life expectancy
Jellice Central Research Institute is promoting research and development of CTP with the finest skills. We believe that CTP is one of the components which extends your healthy life expectancy and brings you a satisfying and wholesome life. We would appreciate opinions by researchers who are interested in the scientific evidence of CTP presented in this website. We also greatly welcome any proposals for new study.
Chairman of Jellice Central Research Institute
